What are the side effects of decitabine?
Decitabine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- excessive tiredness.
- pale skin.
- headache.
- dizziness.
- confusion.
- fast heartbeat.
- difficulty falling asleep or staying asleep.
- weakness.
Can decitabine cure MDS?
Results from phase 2 and phase 3 studies indicate that decitabine is effective in the treatment of MDS, resulting in durable clinical responses and delayed time to AML transformation or death.
How does decitabine work in MDS?
People with MDS may have problems such as infections, anemia, and easy bleeding/bruising. Decitabine is a chemotherapy drug. It is believed to work by helping your bone marrow grow normal blood cells so you will need fewer blood transfusions.
What is the best hospital for MDS?
Expert cancer care. Mayo Clinic in Rochester, Minn., Mayo Clinic in Phoenix/Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked among the Best Hospitals for cancer by U.S. News & World Report.
How long is decitabine infusion?
Dacogen is administered at a dose of 15 mg/m2 by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. This cycle should be repeated every 6 weeks. Patients may be premedicated with standard anti-emetic therapy.
How often is decitabine given?
Decitabine is repeated every 28 days. This is known as one cycle.
Does decitabine cause hair loss?
However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Hair loss. Constipation, diarrhea, stomach pain, upset stomach, throwing up, or feeling less hungry.
What does decitabine do?
This medication is used to treat a group of blood/bone marrow disorders (myelodysplastic syndromes-MDS) in which the bone marrow does not produce enough healthy blood cells. People with MDS may have problems such as infections, anemia, and easy bleeding/bruising. Decitabine is a chemotherapy drug.
